Current Clinical Trials

American Cancer Society VOICES of Black Women

Open

Investigator(s):

Contact:

thevoices@cancer.org or call (800) 494 4113

Sponsor:

Study:

A Phase 4, Observational Study Evaluating the Efficacy and Safety of the Bruton Tyrosine Kinase (BTK) Inhibitor Zanubrutinib in Patients With Waldenström Macroglobulinemia (BGB-3111-402)

A012301-LoTam: A Randomized, Phase III Clinical Trial of Low-Dose Tamoxifen for Selected Patients with Molecular Low-Risk Early-Stage Breast Cancer

Open

Investigator(s):

Delshad Ahmad, MD (primary), Davood Vafai, MD, Henry Tsai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call 760-837-8034

Sponsor:

BeiGene

Study:

National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology

Open

Investigator(s):

Manasa Vulchi, MD (primary), Henry Tsai, MD, Delshad Ahmad, MD, Davood Vafai, MD, Asnakech Bayable, MD

Contact:

Natalie Rocha Casillas Email:CancerReseach@eisenhowerhealth.org or call 760-837-8034

Sponsors:

Study:

A022102-Randomized Phase III Trial of mFOLFIRINOX vs. FOLFOX With Nivolumab for First-Line Treatment of Metastatic HER2- Gastroesophageal Adenocarcinoma

National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology

Open

Investigator(s):

Henry Tsai, MD (primary), Delshad Ahmad, MD

Contact:

cancerresearch@eisenhowerhealth.org or call 760-837-8034

Sponsors:

Study:

HEAL-ABC Harnessing E-Mindfulness Approaches for Living After Breast Cancer (NRG-CC015)

National Cancer Institute (NCI), NRG Oncology

Open

Investigator(s):

Manasa Vulchi, MD (primary)

Contact:

CancerResearch@eisenhowerhealth.org or call 760-837-8034

Sponsors:

Study:

LUNGMAP: A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Lung-Map)

National Cancer Institute (NCI), Bighorn BAM, UCSD-EMC Joint Clinical Trial, SWOG Cancer Research Network

Open

Investigator(s):

Delshad Ahmad, MD (primary), Henry Tsai, MD, Davood Vafai, MD, Amy Law, MD

Contact:

cancerresearch@emc.org or call 760-837-8034

Sponsors:

Study:

NRG-GI008 Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

National Cancer Institute (NCI), NRG Oncology

Open

Investigator(s):

Henry Tsai, MD (primary), Davood Vafai, MD, Delshad Ahmad, MD

Contact:

Natalie Rocha Casillas Email:cancerreseach@eisenhowerhealth.org or call 760-674-3632

Sponsors:

Study:

NRGBR009: A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

S1800E: A Randomized Phase II/III Study of Docetaxel and Ramucirumab with or without Cemiplimab (REGN2810) for Participants Previously Treated with Platinum-based Chemotherapy and Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Non-Matched Sub-Study)

Open

Investigator(s):

Manasa Vulchi, MD (primary)

Contact:

CancerResearch@eisenhowerhealth.org or call 7608378034

Sponsor:

NRG Oncology

Study:

UC San Diego Moores Cancer Center, National Cancer Institute (NCI), SWOG Cancer Research Network

Open

Investigator(s):

Davood Vafai, MD (primary), Delshad Ahmad, MD, Henry Tsai, MD

Contact:

cancerresearch@eisenhowerhealth.org or call 7608378034

Sponsors:

Study:

S1900G A Randomized Phase II Study of INC280 (Capmatinib) Plus Osimertinib With or Without Ramucirumab in Participants With EGFR-Mutant, MET-Amplified Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)

National Cancer Institute (NCI), SWOG Cancer Research Network

Open

Investigator(s):

Delshad Ahmad, MD (primary), Davood Vafai, MD, Henry Tsai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call (760)-837-8034

Sponsors:

Study:

S1900J:A Phase II Study of Amivantamab SC (Subcutaneous) in Participants with MET Amplification-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (LUNG-MAP SUB-STUDY)

Open

Investigator(s):

Delshad Ahmad, MD (primary), Davood Vafai, MD

Contact:

cancerreseach@eisenhowerhealth.org or call 7608378034

Sponsor:

S1900K: A Randomized Phase II Study of Tepotinib with or Without Ramucirumab in Participants with MET Exon 14 Skipping Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (LUNG-MAP SUB-STUDY)

Study:

Open

Investigator(s):

Delshad Ahmad, MD (primary), Davood Vafai, MD, Henry Tsai, MD

Contact:

cancerreseach@eisenhowerhealth.org or call 7608378034

Sponsor:

S2209-A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a Subset of "Intermediate Fit" Comparing Upfront Three-Drug Induction Regimens Followed by Double or Single-Agent Maintenance

Study:

Open

Investigator(s):

Delshad Ahmad, MD (primary), Henry Tsai, MD

Contact:

Valeria Lozano Email:cancerreseach@eisenhowerhealth.org or call 760-837-8034

Sponsor:

UCSD PREDICT - Profile Related Evidence Determining Individualized Cancer Therapy aka Study of Personalized Cancer Therapy to Determine Response and Toxicity. UCSD-HRPP-130794

Study:

UC San Diego Moores Cancer Center, Bighorn BAM, UCSD-EMC Joint Clinical Trial

Open

Investigator(s):

Henry Tsai, MD (primary), Monica Khanna, MD, Delshad Ahmad, MD, Davood Vafai, MD, Nader Kashani, MD

Contact:

cancerresearch@eisenhowerhealth.org or call 760-837-8034

Sponsors:

Study:

Humanitarian Use Device (HUD): Biotronik PK Papyrus Covered Coronary Stent System

The PROGRESS Trial - Continued Access Protocol

Open

Investigator(s):

Puneet Khanna, MD (primary)

Contact:

Puneet Khanna Email:CardiologyResearch@eisenhowerhealth.org or call 760-340-3911

Sponsor:

BIOTRONIK

Study:

Ultrasound-Guided Serratus Anterior Plane Block for Thoracic Trauma: Impact on Opioid Reduction, Morbidity, and Mortality

Open

Investigator(s):

Andrew Frutkin, MD (primary), Praveen Panguluri, MD, Daniel Logsdon, MD

Contact:

Andrew Frutkin Email:cardiologyresearch@eisenhowerhealth.org or call 760-346-0642

Sponsor:

Edwards Lifesciences

Study:

Emergency Medicine

Open

Investigator(s):

Ami Kurzweil, MD (primary), Theresa Kim, MD, Matthew Whited, MD, Michael Hetzel, DO

Contact:

Ami Kurzweil Email:AKurzweil@eisenhowerhealth.org or call 760-773-1221

Sponsor:

Colorectal Cancer in Patients within Screening Age Guidelines Versus Outside of Screening Age Guidelines

Study:

Open

Investigator(s):

Adewale Ajumobi, MD (primary)

Contact:

Adewale Ajumobi Email:AAjumobi@eisenhowerhealth.org or call 760-773-2882

Sponsor:

Post-market Registry Study on the Physica System Total Knee Replacement

Study:

Evaluating the Implications of Initiating Immunotherapy Anti-cancer Treatment in the Inpatient Setting on Patient Outcomes, Treatment Tolerance, and Drug Costs

Open

Investigator(s):

Erik Schnaser, MD (primary), Ghassan Boghosian, DO

Contact:

OrthoResearch@eisenhowerhealth.org or call 760-340-3911

Sponsor:

Enovis

Study:

Pharmacy

Open

Investigator(s):

Contact:

Emily Chang Email:EChang@eisenhowerhealth.org or call 760-837-8336

Sponsor:

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry (PROPEL)

Study:

Galvanize Therapeutics, Inc

Open

Investigator(s):

Justin Thomas, MD (primary)

Contact:

pulmonologyresearch@eisenhowerhealth.org or call 760-340-3911

Sponsors:

Study:

Humanitarian Use Device (HUD): Spiration IBV Valve System.

Retrospective Case Control Study to Examine Timeliness of Care and Outcomes for Lung Cancer Patients When Referred to a Dedicated Interventional Pulmonology Service Versus Interventional Radiology in a Community Hospital

Open

Investigator(s):

Justin Thomas, MD (primary)

Contact:

PulmonologyResearch@eisenhowerhealth.org or call (760)834-8034

Sponsor:

Olympus

Study:

Eisenhower Health Graduate Medical Education (GME), Eisenhower Health

Open

Investigator(s):

Justin Thomas, MD (primary)

Contact:

Noor Alomar Email:NAlomar@eisenhowerhealth.org or call 760-340-3911 x2540

Sponsors:

Study:

A011401 (BWEL Weight Loss Trial): A randomized phase III trial evaluating the role of weight loss in adjuvant treatment of overweight and obese women with early breast cancer.

National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology, Bighorn BAM, UCSD-EMC Joint Clinical Trial

Closed

Investigator(s):

Manasa Vulchi, MD (primary), Henry Tsai, MD, Delshad Ahmad, MD, Davood Vafai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call 760-837-8034

Sponsors:

Study:

A011801-The CompassHER2 Trials (Comprehensive Use of Pathologic Response Assessment to Optimize Therapy in HER2-Positive Breast Cancer) CompassHER2 Residual Disease (RD), a Double-Blinded, Phase III Randomized Trial of T-DM1 Compared With T-DM1 and Tucatinib

Alliance for Clinical Trials in Oncology

Closed

Investigator(s):

Manasa Vulchi, MD (primary), Delshad Ahmad, MD, Henry Tsai, MD, Davood Vafai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call (760) 837-8034

Sponsor:

Study:

A032101: A Phase 2 Trial of ADT Interruption in Patients Responding Exceptionally to AR-Pathway Inhibitor in Metastatic Hormone-Sensitive Prostate Cancer (MHSPC): A-DREAM

National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology

Closed

Investigator(s):

Delshad Ahmad, MD (primary), Henry Tsai, MD, Davood Vafai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call (760) 837-8034

Sponsors:

Study:

ALCHEMIST: Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer (NSCLC) That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial). Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial

National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology, Bighorn BAM, UCSD-EMC Joint Clinical Trial

Closed

Investigator(s):

Davood Vafai, MD (primary), Henry Tsai, MD, Delshad Ahmad, MD

Contact:

cancerresearch@eisenhowerhealth.org or call 760-837-8034

Sponsors:

Study:

E1A11:Randomized Phase III Trial of Bortezomib, LENalidomide and Dexamethasone (VRd) Versus Carfilzomib, Lenalidomide and Dexamethasone (CRd) Followed by Limited or Indefinite DURation Lenalidomide MaintenANCE in Patients with Newly Diagnosed Symptomatic Multiple Myeloma (ENDURANCE)

National Cancer Institute (NCI), ECOG-ACRIN Cancer Research Group

Closed

Investigator(s):

Delshad Ahmad, MD (primary)

Contact:

cancerresearch@emc.org or call 760-837-8034

Sponsors:

Study:

S0931 EVEREST: EVErolimus for Renal Cancer Ensuring Surgical Therapy, A Phase III Study

National Cancer Institute (NCI), SWOG Cancer Research Network

Closed

Investigator(s):

Henry Tsai, MD (primary)

Contact:

research@emc.org or call 760-837-8034

Sponsors:

Study:

S1207 Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/NEU Negative Breast Cancer. e3 Study

National Cancer Institute (NCI), SWOG Cancer Research Network

Closed

Investigator(s):

Amy Law, MD (primary), Henry Tsai, MD, Constantin Dasanu, MD, PhD

Contact:

cancerresearch@emc.org or call 760-837-8034

Sponsors:

Study:

S2010-A Randomized Phase III Trial Comparing Active Symptom Monitoring Plus Patient Education Versus Patient Education Alone to Improve Persistence With Endocrine Therapy in Young Women With Stage I-III Breast Cancer (ASPEN)

Closed

Investigator(s):

Manasa Vulchi, MD (primary), Constantin Dasanu, MD, PhD, Delshad Ahmad, MD, Henry Tsai, MD, Davood Vafai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call (760) 837-8034

Sponsor:

S2013: Immune Checkpoint Inhibitor Toxicity (I-CHECKIT): A Prospective Observational Study

Study:

Closed

Investigator(s):

Henry Tsai, MD (primary), Delshad Ahmad, MD, Henry Tsai, MD, Davood Vafai, MD

Contact:

CancerResearch@eisenhowerhealth.org or call (760) 837-8034

Sponsor:

Strategic Targeting for Optimal Prevention of Cancer (STOP-Cancer)

Study:

Closed to Enrollment September 19, 2025 CONVERGE Post-Approval Study (PAS): Hybrid Convergent of Epicardial and Endocardial RF Ablation for the Treatment of Symptomatic Longstanding Persistent AF

Closed

Investigator(s):

Contact:

CancerResearch@eisenhowerhealth.org or call (760)-837-8034

Sponsor:

Study:

CLOSED TO ENROLLMENT: CHAMPION-AF: WATCHMAN FLX versus NOAC for EMbolic Protection in the Management of Patients with Non-Valvular Atrial Fibrillation

Closed

Investigator(s):

Daniel Logsdon, MD (primary), Joseph Wilson, MD, Leon Feldman, MD, Andrew Rubin, MD, Evangelos Diamantakos, DO

Contact:

Daniel Logsdon Email:cardiologyresearch@eisenhowerhealth.org or call 760-346-0642

Sponsor:

AtriCure

Study:

CLOSED TO ENROLLMENT: LIBREXIA-AF: A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, Versus Apixaban in Participants With Atrial Fibrillation.

Closed

Investigator(s):

Leon Feldman, MD (primary), Andrew Rubin, MD, Evangelos Diamantakos, DO

Contact:

Leon Feldman Email:CardiologyResearch@eisenhowerhealth.org or call 760-346-0642

Sponsor:

Boston Scientific

Study:

CLOSED TO ENROLLMENT: PROGRESS: A Prospective, Randomized, Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement (TAVR)

Closed

Investigator(s):

Andrew Rubin, MD (primary), Leon Feldman, MD, Evangelos Diamantakos, DO, Jon Sherman, MD

Contact:

Andrew Rubin Email:CardiologyResearch@eisenhowerhealth.org or call 760-346-0642

Sponsor:

Janssen

Study:

PENN+PLUS CC: University of Pennsylvania+ PLUS Clinical Center(PENN+PLUS CC). 5U01DK106892-09

Closed

Investigator(s):

Andrew Frutkin, MD (primary), Praveen Panguluri, MD, Daniel Logsdon, MD

Contact:

Andrew Frutkin Email:CardiologyResearch@eisenhowerhealth.org or call 760-346-0642

Sponsor:

Edwards Lifesciences

Study:

Infectious Disease

Closed

Investigator(s):

Ann Stapleton, MD (primary)

Contact:

astapleton@eisenhowerhealth.org or call 760-834-7950

Sponsors:

University of Pennsylvania, NIH National Institute of Diabetes and Digestive and Kidney Diseases-PENN+PLUS CC

Study:

A Clinical Study to Assess the Safety and Effectiveness of the Premia Spine TOPS™ System

A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/ Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted

Closed

Investigator(s):

Amir Tahernia, MD (primary)

Contact:

OrthoResearch@eisenhowerhealth.org or call 760-340-3911 x2511

Sponsor:

Premia Spine

Study:

INFINITY™ With ADAPTIS™ Technology Total Ankle Replacement Follow-Up (ITAR2)

Closed

Investigator(s):

Erik Schnaser, MD (primary)

Contact:

orthoresearch@eisenhowerhealth.org or call 760-340-3911 x2511

Sponsors:

Smith & Nephew, Inc

Study:

Pathogenesis of Rheumatic Disease

Closed

Investigator(s):

David Friscia, MD (primary)

Contact:

OrthoResearch@eisenhowerhealth.org or call 760-340-3911 x2540

Sponsor:

Stryker

Study:

University of California San Diego

Closed

Investigator(s):

Erik Schnaser, MD (primary)

Contact:

OrthoResearch@eisenhowerhealth.org or call 760-340-3911 x2540

Sponsor:

Study:

Quality Initiative: American Joint Replacement Registry (AJRR).

American Joint Replacement Registry

Closed

Investigator(s):

Erik Schnaser, MD (primary)

Contact:

orthoresearch@eisenhowerhealth.org or call 760-340-3911

Sponsor:

Study:

Tornier Perform® Humeral System - Fracture Study (PFX)

Auto Pleurodesis Rates in Patients with Malignant Pleural Effusions with PleurX Placement

Closed

Investigator(s):

David Savin, MD (primary), Karimdad Otarodi, MD

Contact:

OrthoResearch@eisenhowerhealth.org or call 760-340-3911

Sponsor:

Stryker

Study:

Closed

Investigator(s):

Justin Thomas, MD (primary)

Contact:

PulmonologyResearch@eisenhowerhealth.org or call (760)834-8034

Sponsor:

CBCT Guidance in MONARCH Robotic Assisted Bronchoscopy: Single center experience using Cone Beam CT Guidance in Monarch robotic bronchoscopy: Challenges and Outcomes

Study:

Closed

Investigator(s):

Justin Thomas, MD (primary)

Contact:

pulmonologyresearch@eisenhowerhealth.org or call 760-837-8034

Sponsor:

Evaluating the Diagnostic Yield of Peripheral Nodules Using Electromagnetic Navigational Bronchoscopy

Study:

Closed

Investigator(s):

Justin Thomas, MD (primary)

Contact:

PulmonologyResearch@eisenhowerhealth.org or call (760)834-8034

Sponsor:

MONARCH - Robotic Assisted Bronchoscopy Protocol Single center experience in adoption of a robotic bronchoscope: Challenges and outcomes

Study:

Closed

Investigator(s):

Justin Thomas, MD (primary)

Contact:

PulmonologyResearch@eisenhowerhealth.org or call (760)834-8034

Sponsor:

The Role of Surveillance Bronchoscopies in Bronchial Stents

Study:

Closed

Investigator(s):

Justin Thomas, MD (primary)

Contact:

PulmonologyResearch@eisenhowerhealth.org or call (760)834-8034

Sponsor:

Evaluating the effectiveness of copper-fabricated surfaces in reducing healthcare-associated infections in the intensive care unit.

Study:

Quality

Closed

Investigator(s):

Eric Leroux, MD (primary)

Contact:

Theresa Perez Email:TPerez@eisenhowerhealth.org or call 760-340-3911 x6222

Sponsor: